![]() Investigators also suggested further research on how ABO status may moderate venous thromboembolism occurrence, a known complication of COVID-19, since blood group O patients have been associated with a decreased risk of venous thromboembolism in prior research. “Furthermore, among ongoing clinical trials of immunotherapy using convalescent plasma or of SARS-CoV-2 vaccines, the interaction between participant blood groups and therapeutic efficacy could be measured.” “Studies of the accuracy of serologic tests for anti-SARS-CoV-2 immunoglobulins may assess whether there is variation in antibody titers by ABO and Rh status,” the authors noted. The O- blood group did not appear protective against severe COVID-19 illness and death (aRR, 0.84 95% CI, 0.64-1.07) compared with other blood groups. Secondary outcome results indicated that type O blood group had an aRR of 0.87 (95% CI, 0.78-0.97) for severe COVID-19 illness and death versus all other blood groups and Rh- status had an aRR of 0.82 (95% CI, 0.68–0.96) compared to Rh+ status. The relative protective effects of O, Rh-, and O- blood groups were greatest in patients younger than age 70. Results also indicated the aRR for SARS-CoV-2 infection was higher in patients with AB blood type compared with type A. Comparatively, the highest unadjusted probability of SARS-CoV-2 infection was in the B+ blood group (4.2% 95% CI, 4.0-4.5%). The aRR for SARS-CoV-2 infection in the O blood group was 0.88 (95% CI, 0.84-0.92) vs all other blood groups, and the ARD was -3.9 per 1,000 (95% CI, -5.4 to -2.5). The O- blood group had a 2.1% chance of getting SARS-CoV-2 infection (95% CI, 1.8-2.3%), the lowest unadjusted probability of all blood groups. For the primary outcome, analyses were further stratified by patients aged younger than 70 years vs 70 years or older. Adjusted relative risks (aRRs) and absolute risk differences (ARDs) were adjusted for demographic characteristics and comorbidities. The secondary outcome was severe COVID-19 illness or death. The study’s primary outcome was SARS-CoV-2 infection. Common comorbidities included preexisting cardiac disease (13-15%), chronic kidney disease (11%), anemia (21%), cancer (27-29%), dementia or frailty (33-38%), diabetes mellitus (21%), asthma (18-21%), and chronic hypertension (39-41%). The mean age was 53.8 years and 29% were men. ![]() Investigators conducted a population-based, retrospective cohort study of 225,556 patients who had their ABO blood group assessed between January 2007 and December 2019, and subsequently tested for SARS-CoV-2 between January 15 and June 30, 2020. Interested in finding out what blood type you are?ĭon’t know your blood type? We’ll test your blood when you donate and let you know your type.Patients with type O and rhesus negative (Rh-) blood groups may have a lower risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and severe coronavirus disease 2019 (COVID-19) illness, according to a study published in the Annals of Internal Medicine. While having O negative blood makes you a universal blood donor, it also means that if you need blood, you can only be transfused with O negative blood. Not only will you help save lives, but you’ll also ensure there’s a good supply of O negative available should you need blood. If you have O negative blood and are able to donate, we encourage you to do so. ![]() What does this mean for those with O negative blood? O negative blood may not be the rarest blood type, but may be critical to a victim’s survival in an emergency. When trauma victims need urgent treatment, there is seldom time to test their blood type, so O negative blood is used. In addition, emergency services, including ambulances and helicopters, may also carry it to keep patients alive while they’re being transported to a hospital. Hospitals need to have it on hand for emergencies. O negative blood is valuable because it can be transfused to anyone, regardless of their blood type. If O negative isn’t that rare, why do blood centers and hospitals always need it? Fewer than 50 people in the entire world population are known to have Rh-null blood. However, the rarest blood type in the world is Rh-null, which is so rare most of us have never heard of it. Is that rare? Only about 1 in 67 have B negative blood, making it rarer. Or to put it another way, about 1 in 15 people have O negative blood. If you have 0 negative blood, you have something in common with about 7 percent of the US population. People with O negative blood often wonder how rare their blood is since it is always in demand by hospitals and blood centers.
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